Tadalafil Study Finds Muscle Cell Boost in Mice but Delayed Maturation A new study in Molecular Biology Reports found that tadalafil, the active ingredient in Cialis, increased muscle precursor cells in mouse muscle cells but delayed their maturation into muscle fibers, and experts caution it does not prove the drug builds muscle in humans. A new laboratory study has found that tadalafil, the active ingredient in the erectile dysfunction pill Cialis, may support muscle tissue repair and regeneration by increasing muscle precursor cells, though it also delayed their maturation into fully functional muscle fibers. The research was published in the journal Molecular Biology Reports and tested the drug on mouse muscle cells in a laboratory setting. The study found that tadalafil increased the number of muscle precursor cells, which are involved in the early stages of muscle formation, and helped more of them survive.Tadalafil Delays Mature Muscle Cell DevelopmentHowever, despite these positive outcomes, the research found that tadalafil delayed the development of fully mature muscle cells. This suggests that the drug could create and maintain more cells involved in muscle regeneration, but does not indicate an increase in muscle size and function in humans. As the study was conducted in mouse models, the results may differ when applied to humans, posing a limitation to the study findings.Study co-author Dr. Cristina Antinozzi, a researcher in the Endocrinology Unit at the University of Rome Foro Italico, said these findings represent an encouraging look at how tadalafil might be repurposed to support muscle tissue repair and regeneration. She added that this is a fascinating biological signal, but it is far from proving that Cialis builds muscle or improves recovery in people.Antinozzi also said that while more work is needed, this research opens up exciting new possibilities for future therapeutic strategies in muscle recovery, though it also highlights the need to monitor how such mechanisms might be viewed or misused. Dr. Kien Vuu, a radiologist and founder of VuuMD Performance and Longevity in Los Angeles, who was not involved in the study, agreed that this is an intriguing early finding.He told Fox News Digital that the active ingredient in Cialis helped muscle precursor cells grow and survive, but also delayed their maturation into muscle fibers. Vuu added that successful regeneration ultimately requires those cells to mature and form functional muscle tissue, and this experiment did not establish that outcome.Experts Warn Against Using Cialis For Muscle BuildingHe emphasized that this was a laboratory cell study, not a clinical trial, and that we need animal studies and eventually human trials examining actual muscle mass, strength, physical function and safety before drawing conclusions about clinical use. He concluded that people should not take it for muscle-building based on these findings.Jacob Zemer, a New York-based fitness coach who primarily trains clients ranging from 35 to 55 years old, said there are several reasons that adults start losing muscle as they get older. Resistance training, adequate protein and quality sleep remain the most reliable ways to protect muscle with age, according to an expert. A separate article noted that Viagra could do more than advertised as a study reveals a surprising health superpower.Other health news includes a new belly fat injection that cuts dangerous fat surrounding organs by 12% in an early human trial, and one type of sleep linked to dramatically lower risk of dementia, Parkinson's and 81 other diseases.